Hydrocholeretic

Hydrocholeretics are substances that increase the volume of secretion of bile from the liver without increasing the amount of solids secreted.^[1] Some substances can result in decreased solid production, possibly due to circulatory effects.^[2]

Cyclobutyrol is a compound commonly used as a hydrocholeretic. Its effects in rats include a dose-dependent increase in bile flow, sodium, potassium, chloride and bicarbonate outputs and reduced bile acid concentrations.^[3]