Hydrophilization

Hydrophilization is a process used on hydrophobic drugs to increase their release rate from capsules, which depends on the rate of dissolution, by covering the surfaces of their particles with minute droplets of a dissolved hydrophilic polymer (such as methyl cellulose or hydroxyethyl cellulose).^[1][2] In tablet or capsule formulations, this enhances the dissolution and disintegration of the drug.^[2]