Hydrophosphonylation

In chemistry hydrophosphonylation refers to any reaction where addition across a double bond generates a phosphonate (RP(O)(OR')₂) group.^[1] Examples include the Kabachnik–Fields reaction, where a dialkylphosphite reacts across an imine to form an aminophosphonate. The reaction is catalyzed by bases and is subject to organocatalysis.^[2][3] Important compounds generated by this reaction include the common herbicide glyphosate.

Hydrophosphonylation reactions

• Kabachnik–Fields reaction
• Pudovik reaction
• Abramov reaction

See also

• Hydrophosphination - the addition of a phosphine derivative (PHR₂) across a double bond