INDO

This article is about a method in computational chemistry. For the human INDO gene, see Indoleamine 2,3-dioxygenase.

INDO stands for Intermediate Neglect of Differential Overlap. It is a semi-empirical quantum chemistry method that is a development of the complete neglect of differential overlap (CNDO/2) method introduced by John Pople. Like CNDO/2 it uses zero-differential overlap for the two-electron integrals but not for integrals that are over orbitals centered on the same atom.^[1][2]

The method is now rarely used in its original form with some exceptions^[3] but it is the basis for several other methods, such as MINDO, ZINDO and SINDO.

See also

• Computational chemistry