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Iberdomide

Chemical compound From Wikipedia, the free encyclopedia

Iberdomide
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Iberdomide (CC-220) is an experimental thalidomide analog[1] that works as an cereblon E3 ligase modulator; it has a higher binding affinity than lenalidomide or pomalidomide. It is developed by Bristol Myers Squibb for various cancers[2][3][4][5][6][7][8] and was also tested in people with lupus.[9]

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Iberdomide has been tested in combination with Bi-specific T-cell engagers in the B-Cell Non-Hodgkin Lymphoma setting,[10] but has been dropped in favor of Golcadomide (CC-99282).

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