Ifoxetine

Ifoxetine
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name (3R,4S)-4-(2,3-dimethylphenoxy)piperidin-3-ol;
CAS Number	66208-11-5;
PubChem CID	71971;
ChemSpider	64977;
UNII	LHH887104B;
ChEMBL	ChEMBL2218865;
CompTox Dashboard (EPA)	DTXSID10216397 ;
Chemical and physical data
Formula	C13H19NO2
Molar mass	221.300 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O(c1cccc(c1C)C)[C@H]2CCNC[C@H]2O;

Ifoxetine (CGP-15,210-G) is a selective serotonin reuptake inhibitor (SSRI) which was investigated as an antidepressant in the 1980s but was never marketed.^[1]^[2]^[3] Ifoxetine selectively blocks the reuptake of serotonin in the brain supposedly without affecting it in the periphery.^[3] Supporting this claim, ifoxetine was found to be efficacious in clinical trials and was very well tolerated, producing almost no physical side effects or other complaints of significant concern.^[3]

Quick facts Clinical data, Routes ofadministration ...

References