Influenza non-structural protein

Influenza non-structural protein (NS1) is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA.^[1]

Influenza non-structural protein (NS1)
Identifiers
Symbol	Flu_NS1
Pfam	PF00600
InterPro	IPR000256
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary PDB PDB: 1ail​ PDB: 1ns1​