Ipidacrine

Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound is a modification of the older drug tacrine (Cognex).^[1]

Ipidacrine

Clinical data
Trade names	Neiromidin
Other names	Amiridine; NIK-247
ATC code	N06DA05 (WHO)
Legal status
Legal status	US: Unscheduled Not FDA approved
Identifiers
IUPAC name 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine
CAS Number	62732-44-9
PubChem CID	604519
ChemSpider	525510
UNII	CV71VTP0VN
ChEMBL	ChEMBL130880
CompTox Dashboard (EPA)	DTXSID7048299
ECHA InfoCard	100.201.385
Chemical and physical data
Formula	C12H16N2
Molar mass	188.274 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CCc2c(c(c3c(n2)CCC3)N)C1
InChI InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14) Key:YLUSMKAJIQOXPV-UHFFFAOYSA-N

Ipidacrine is a reversible acetylcholinesterase inhibitor used in memory disorders of different origins.^[2][3][4]

Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.^[5]

See also

• List of Russian drugs