Isotocyanozene

Isotocyanozene (5-cyano-isotodesnitazene) is a benzimidazole opioid analogue of isotonitazene which has been sold as a designer drug. It was first reported in the Scotland, United Kingdom in 2025, and is presumed to have opioid effects.^[1] It has been identified by the drug checking service CanTEST, Australia in September 2025 as an expected 'opioid' sample, and then later as an expected 'benzodiazepine' sample.^[2][3] The relative activity of this benzimidazole opioid 'desnitazene' analogue is unknown.

Isotocyanozene

Identifiers
IUPAC name 1-[2-(diethylamino)ethyl]-2-[(4-prop-2-yloxyphenyl)methyl]benzimidazole-5-carbonitrile
Chemical and physical data
Formula	C24H30N4O
Molar mass	390.531 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)Oc1ccc(cc1)Cc1nc2cc(ccc2n1CCN(CC)CC)C#N

See also

• Etocyanozene
• Etomethazene
• Isotonitazene
• List of benzimidazole opioids