IsrM small RNA

The IsrM RNA is a small non-coding RNA discovered in Salmonella enterica pathogenicity island, which is not found in E. coli.^[1] It is important for invasion of epithelial cells, intracellular replication inside macrophages, virulence and colonisation in mice. It targets the SopA and HilE mRNAs, virulence factors essential for bacterial invasion. It is a first pathogenicity island-encoded sRNA shown to be directly involved in Salmonella pathogenesis.^[2]

IsrM sRNA
Predicted secondary structure and sequence conservation of IsrM small RNA
Identifiers
Rfam	RF02763
Other data
Domain	Bacteria
GO	GO:0009405 ,GO:0040033
SO	SO:0000370
PDB structures	PDBe