JZ-IV-10

JZ-IV-10 is a piperidine derivative related to cocaine which acts as a highly potent serotonin–norepinephrine–dopamine reuptake inhibitor (also called SNDRI, or triple reuptake inhibitor).^[1] The eugeroic modafinil was used as a lead to fuel this compound's discovery.^[2][3]

JZ-IV-10

Identifiers
IUPAC name (+)-2-([(3R,4S)-1-methyl-4-(4-chlorophenyl)piperidin-3-yl]methylthio)-N-isopropylacetamide
CAS Number	807342-16-1 N
PubChem CID	11291199
ChemSpider	9466185 N
UNII	GYT6ACY5JL
CompTox Dashboard (EPA)	DTXSID201028809
Chemical and physical data
Formula	C18H27ClN2OS
Molar mass	354.94 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc1ccc(cc1)[C@H]2CCN(C)C[C@@H]2CSCC(=O)NC(C)C
InChI InChI=1S/C18H27ClN2OS/c1-13(2)20-18(22)12-23-11-15-10-21(3)9-8-17(15)14-4-6-16(19)7-5-14/h4-7,13,15,17H,8-12H2,1-3H3,(H,20,22)/t15-,17-/m1/s1 N Key:GPNABXAHBDYHFE-NVXWUHKLSA-N N
NY (what is this?)  (verify)

See also

• 1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
• JJC8-088
• N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate
• Nocaine