JZL195

JZL195 is a potent inhibitor of both fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), the primary enzymes responsible for degrading the endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively.^[1]

JZL195

Names
Preferred IUPAC name 4-Nitrophenyl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate
Identifiers
CAS Number	1210004-12-8
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL606201
ChemSpider	24655100
PubChem CID	46232606
UNII	TP6P2HKJ54 Y
CompTox Dashboard (EPA)	DTXSID401029877
InChI InChI=1S/C24H23N3O5/c28-24(32-22-11-9-20(10-12-22)27(29)30)26-15-13-25(14-16-26)18-19-5-4-8-23(17-19)31-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2 Key: QNYRAEKLMNDRFY-UHFFFAOYSA-N
SMILES c1ccc(cc1)Oc2cccc(c2)CN3CCN(CC3)C(=O)Oc4ccc(cc4)[N+](=O)[O-]
Properties
Chemical formula	C24H23N3O5
Molar mass	433.464 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

See also

• JZL184
• JNJ-42165279