Kelch-like protein 1

Kelch-like protein 1 is a protein that in humans is encoded by the KLHL1 gene.^[5][6]

KLHL1
Identifiers
Aliases	KLHL1, MRP2, kelch like family member 1
External IDs	OMIM: 605332; MGI: 2136335; HomoloGene: 56903; GeneCards: KLHL1; OMA:KLHL1 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q21.33 Start 69,700,594 bp[1] End 70,108,493 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 E2.1 Start 96,340,172 bp[2] End 96,756,538 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pars reticulata pars compacta testicle superior vestibular nucleus ventral tegmental area pons hypothalamus islet of Langerhans ganglionic eminence prefrontal cortex Top expressed in ventral tegmental area substantia nigra lumbar subsegment of spinal cord lateral hypothalamus habenula ventromedial nucleus mammillary body supraoptic nucleus central gray substance of midbrain medial vestibular nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function ubiquitin-protein transferase activity actin binding Cellular component Cul3-RING ubiquitin ligase complex cytoskeleton dendrite soma cytoplasm Biological process cerebellar Purkinje cell layer development actin cytoskeleton organization locomotory behavior adult walking behavior dendrite development protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57626 93688 Ensembl ENSG00000150361 ENSMUSG00000022076 UniProt Q9NR64 Q9JI74 RefSeq (mRNA) NM_020866 NM_001286725 NM_053105 RefSeq (protein) NP_001273654 NP_065917 NP_444335 Location (UCSC) Chr 13: 69.7 – 70.11 Mb Chr 14: 96.34 – 96.76 Mb PubMed search [3] [4]
Wikidata
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