Kelch-like protein 2

Kelch-like family member 2 is a protein that in humans is encoded by the KLHL2 gene.^[5]

KLHL2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2XN4, 4CHB
Identifiers
Aliases	KLHL2, ABP-KELCH, MAV, MAYVEN, kelch like family member 2
External IDs	OMIM: 605774; MGI: 1924363; HomoloGene: 21416; GeneCards: KLHL2; OMA:KLHL2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q32.3 Start 165,207,561 bp[1] End 165,323,156 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.1 Start 65,192,709 bp[2] End 65,302,669 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 Region I of hippocampus proper postcentral gyrus optic nerve external globus pallidus superior frontal gyrus middle temporal gyrus dorsal motor nucleus of vagus nerve Brodmann area 46 orbitofrontal cortex Top expressed in olfactory tubercle nucleus accumbens dentate gyrus subdivision of hippocampus globus pallidus Region I of hippocampus proper primary motor cortex hippocampus proper piriform cortex cumulus cell More reference expression data BioGPS n/a
Gene ontology Molecular function ubiquitin-protein transferase activity protein binding actin binding identical protein binding Cellular component ruffle cell projection actin cytoskeleton lamellipodium cytoskeleton cytoplasm Cul3-RING ubiquitin ligase complex cytosol Biological process protein ubiquitination post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11275 77113 Ensembl ENSG00000109466 ENSMUSG00000031605 UniProt O95198 Q8JZP3 RefSeq (mRNA) NM_001161521 NM_001161522 NM_007246 NM_001331023 NM_001331024 NM_178633 RefSeq (protein) NP_001154993 NP_001154994 NP_001317952 NP_001317953 NP_009177 NP_848748 Location (UCSC) Chr 4: 165.21 – 165.32 Mb Chr 8: 65.19 – 65.3 Mb PubMed search [3] [4]
Wikidata
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