Kelch-like protein 8

Kelch-like protein 8 is a protein that in humans is encoded by the KLHL8 gene.^[5]

KLHL8
Identifiers
Aliases	KLHL8, kelch like family member 8
External IDs	OMIM: 611967; MGI: 2179430; HomoloGene: 10819; GeneCards: KLHL8; OMA:KLHL8 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q22.1 Start 87,160,103 bp[1] End 87,240,314 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 E5|5 50.45 cM Start 104,009,839 bp[2] End 104,059,125 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis secondary oocyte tail of epididymis deltoid muscle caput epididymis Skeletal muscle tissue of biceps brachii tibialis anterior muscle trabecular bone Skeletal muscle tissue of rectus abdominis mucosa of ileum Top expressed in primary oocyte zygote secondary oocyte triceps brachii muscle knee joint vastus lateralis muscle temporal muscle spermatocyte sternocleidomastoid muscle spermatid More reference expression data BioGPS n/a
Gene ontology Molecular function ubiquitin-protein transferase activity Cellular component Cul3-RING ubiquitin ligase complex nucleoplasm Biological process protein ubiquitination ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57563 246293 Ensembl ENSG00000145332 ENSMUSG00000029312 UniProt Q9P2G9 P59280 RefSeq (mRNA) NM_001292003 NM_001292006 NM_001292007 NM_020803 NM_178741 NM_001359986 NM_001359987 RefSeq (protein) NP_001278932 NP_001278935 NP_001278936 NP_065854 NP_848856 NP_001346915 NP_001346916 Location (UCSC) Chr 4: 87.16 – 87.24 Mb Chr 5: 104.01 – 104.06 Mb PubMed search [3] [4]
Wikidata
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