Keratin 15

Keratin 15 is a protein that in humans is encoded by the KRT15 gene.^[5][6] It has also been referred to as cytokeratin 15, K1CO and KRTB.

KRT15
Identifiers
Aliases	KRT15, CK15, K15, K1CO, keratin 15
External IDs	OMIM: 148030; MGI: 96689; HomoloGene: 1712; GeneCards: KRT15; OMA:KRT15 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,513,745 bp[1] End 41,522,529 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 D|11 63.41 cM Start 100,022,584 bp[2] End 100,026,754 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of pharynx skin of thigh skin of arm skin of abdomen epithelium of nasopharynx gums gingival epithelium cervix epithelium vulva skin of hip Top expressed in conjunctival fornix skin of abdomen lip esophagus transitional epithelium of urinary bladder skin of external ear cornea skin of back umbilical cord trachea More reference expression data BioGPS n/a
Gene ontology Molecular function scaffold protein binding structural constituent of cytoskeleton protein binding structural molecule activity Cellular component extracellular exosome intermediate filament nucleus cytosol Biological process epidermis development cytoskeleton organization keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3866 16665 Ensembl ENSG00000171346 ENSMUSG00000054146 UniProt P19012 Q61414 RefSeq (mRNA) NM_002275 NM_008469 RefSeq (protein) NP_002266 NP_032495 Location (UCSC) Chr 17: 41.51 – 41.52 Mb Chr 11: 100.02 – 100.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Keratin 15 is a type I cytokeratin. It is well-expressed in the basal layer of complex epithelia. However, acral keratinocytes express little to no keratin 15.^[7]