Keratin 34

Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene.^[5][6][7][8]

KRT34
Identifiers
Aliases	KRT34, HA4, Ha-4, KRTHA4, hHa4, Keratin 34, K34
External IDs	OMIM: 602763; MGI: 1309994; HomoloGene: 31083; GeneCards: KRT34; OMA:KRT34 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,377,669 bp[1] End 41,382,306 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 D|11 63.38 cM Start 99,928,173 bp[2] End 99,932,380 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle stromal cell of endometrium placenta skin of abdomen ectocervix skin of leg vagina canal of the cervix right lung mucosa of esophagus Top expressed in lip skin of back hair follicle skin of abdomen dermis skin of external ear sexually immature organism conjunctival fornix medial head of gastrocnemius muscle foregut More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity Cellular component intermediate filament extracellular exosome extracellular space cytosol Biological process epidermis development keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3885 16672 Ensembl ENSG00000131737 ENSG00000262045 ENSMUSG00000043485 UniProt O76011 Q9D646 RefSeq (mRNA) NM_021013 NM_001386014 NM_027563 RefSeq (protein) NP_066293 NP_081839 Location (UCSC) Chr 17: 41.38 – 41.38 Mb Chr 11: 99.93 – 99.93 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.^[8]

See also

• 34βE12 (keratin 903)