L-fuculose-phosphate aldolase

The enzyme L-fuculose-phosphate aldolase (EC 4.1.2.17) catalyzes the chemical reaction

L-fuculose-1-phosphate ${\displaystyle \rightleftharpoons }$ glycerone phosphate^[1] + (S)-lactaldehyde

L-fuculose-phosphate aldolase
Identifiers
EC no.	4.1.2.17
CAS no.	9024-54-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-fuculose-1-phosphate (S)-lactaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include L-fuculose 1-phosphate aldolase, fuculose aldolase, and L-fuculose-1-phosphate lactaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.

Structural studies

As of late 2007, 20 structures have been solved for this class of enzymes, with PDB accession codes 1DZU, 1DZV, 1DZW, 1DZX, 1DZY, 1DZZ, 1E46, 1E47, 1E48, 1E49, 1E4A, 1E4B, 1E4C, 1FUA, 2FK5, 2FLF, 2FUA, 2OPI, 3FUA, and 4FUA.

See also

• Fuculose
• L-Fuculose kinase