L-myc internal ribosome entry site (IRES)

The L-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of L-myc that allows cap-independent translation. L-myc undergoes translation via the internal ribosome entry site and bypasses the typical eukaryotic cap-dependent translation pathway [1]. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis.

L-myc internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_L-myc
Identifiers
Symbol	IRES_L-myc
Rfam	RF00261
Other data
RNA type	Cis-reg; IRES
Domain(s)	Eukaryota
GO	GO:0043022
SO	SO:0000243
PDB structures	PDBe