LL-100 panel

The LL-100 panel is a group of 100 human leukemia and lymphoma cell line,^[1] can be used in model of biomedical research.^[2]

Purpose

LL-100 panel cell lines cover the full spectrum of human leukemia and lymphoma including T-cell, B-cell and myeloid malignancies.^[1]

List of LL-100 cell lines

Pre-B-ALL

Cell line	Sex	Age	Ref	Cellosaurus
697	Male	12Y	[3]	CVCL_0079
KOPN-8	Female	3M	[4]	CVCL_1866
NALM-6	Male	19Y	[5]	CVCL_0092
REH	Female	15Y	[6]	CVCL_1650
SEM	Female	5Y	[7]	CVCL_0095

B-NHL: Burkitt/B-ALL

Cell line	Sex	Age	Ref	Cellosaurus
BJAB [zh]	Female	5Y	[8]	CVCL_5711
Daudi cell [zh]	Male	16Y	[9]	CVCL_0008
Raji	Male	11Y	[10]	CVCL_0511
RAMOS	Male	3Y	[11]	CVCL_0597
VAL	Female	50Y	[12]	CVCL_1819

B-NHL: CLL/PLL

Cell line	Sex	Age	Ref	Cellosaurus
HG-3	Male	70Y	[13]	CVCL_Y547
JVM-3	Male	73Y	[14]	CVCL_1320
JVM-13	Male	60-69Y	[15]	CVCL_1318
MEC-1	Male	61Y	[16]	CVCL_1870
PGA-1	Male	unspecified	[17]	CVCL_Y545

B-NHL: DLBCL ABC

Cell line	Sex	Age	Ref	Cellosaurus
NU-DHL-1	Male	73Y	[18]	CVCL_1876
OCI-Ly3	Male	52Y	[19]	CVCL_8800
Ri-1	Female	57Y	[20]	CVCL_1885
U-2932	Female	29Y	[21]	CVCL_1896
U-2946	Male	52Y	[22]	CVCL_X503

B-NHL: DLBCL GC

Cell line	Sex	Age	Ref	Cellosaurus
DoHH2	Male	60Y	[23]	CVCL_1179
OCI-Ly7	Male	48Y	[19]	CVCL_1881
OCI-Ly19	Female	27Y	[24]	CVCL_1878
SU-DHL-4	Male	38Y	[25]	CVCL_0539
SU-DHL-6	Male	43Y	[25]	CVCL_2206
WSU-DLCL2	Male	41Y	[26]	CVCL_1902

B-NHL: HCL

Cell line	Sex	Age	Ref	Cellosaurus
BONNA-12	Male	46Y	[27]	CVCL_1090
Hair-M	Male	86Y	[28]	CVCL_B401
HC-1	Male	56Y	[29]	CVCL_1243

B-NHL: MCL

Cell line	Sex	Age	Ref	Cellosaurus
Granta-519	Female	58Y	[30]	CVCL_1818
JeKo-1	Female	78Y	[31]	CVCL_1865
JVM-2	Female	63Y	[14]	CVCL_1319
Mino	Male	68Y	[32]	CVCL_1872
REC-1	Male	61Y	[33]	CVCL_1884

B-NHL: PEL

Cell line	Sex	Age	Ref	Cellosaurus
BC-3	Male	85Y	[34]	CVCL_1080
BCBL-1	Male	40Y	[35]	CVCL_0165
CRO-AP2	Male	49Y	[36]	CVCL_1147
CRO-AP5	Male	35Y	[37]	CVCL_1148

B-NHL: PMBL

Cell line	Sex	Age	Ref	Cellosaurus
U-2940	Female	18Y	[38]	CVCL_1897

Multiple myeloma/PCL

Cell line	Sex	Age	Ref	Cellosaurus
KMS-12-BM	Female	64Y	[39]	CVCL_1334
L-363	Female	36Y	[40]	CVCL_1357
LP-1	Female	56Y	[41]	CVCL_0012
OPM-2	Female	56Y	[42]	CVCL_1625
RPMI-8226	Male	61Y	[43]	CVCL_0014
U-266	Male	53Y	[44]	CVCL_0566

Hodgkin lymphoma

Cell line	Sex	Age	Ref	Cellosaurus
HDLM-2	Male	74Y	[45]	CVCL_0009
KM-H2	Male	37Y	[46]	CVCL_1330
L-428	Female	37Y	[45]	CVCL_1361
L-1236	Male	34Y	[47]	CVCL_2096
SUP-HD1	Male	37Y	[48]	CVCL_2208

T-ALL/T-LL

Cell line	Sex	Age	Ref	Cellosaurus
CCRF-CEM [zh]	Female	3Y11M	[49]	CVCL_0207
DND-41 [zh]	Male	13Y	[50]	CVCL_2022
HPB-ALL	Male	14Y	[51]	CVCL_1820
Jurkat	Male	14Y	[52]	CVCL_0065
MOLT-4	Male	19Y	[53]	CVCL_0013
RPMI-8402	Female	16Y	[54]	CVCL_1667

Mature T-malignancy

Cell line	Sex	Age	Ref	Cellosaurus
DERL-7	Male	30Y	[55]	CVCL_2017
HH	Male	61Y	[56]	CVCL_1280
MOTN-1	Female	65Y	[57]	CVCL_2127

NK malignancy

Cell line	Sex	Age	Ref	Cellosaurus
KHYG-1	Female	45Y	[58]	CVCL_2976
NK-92	Male	50Y	[59]	CVCL_2142
YT	Male	15Y	[60]	CVCL_1797

ALCL

Cell line	Sex	Age	Ref	Cellosaurus
DEL	Male	12Y	[61]	CVCL_1170
SR-786	Male	11Y	[62]	CVCL_1711
SU-DHL-1	Male	10Y	[63]	CVCL_0538
SUP-M2	Female	5Y	[64]	CVCL_2209

AML myelocytic

Cell line	Sex	Age	Ref	Cellosaurus
EoL-1 [zh]	Male	33Y	[65]	CVCL_0258
HL-60	Female	36Y	[66]	CVCL_0002
Kasumi-1	Male	7Y	[67]	CVCL_0589
KG-1 [zh]	Male	59Y	[68]	CVCL_0374
NB4	Female	23Y	[69]	CVCL_0005
OCI-AML3	Male	57Y	[70]	CVCL_1844
SKNO-1	Male	22Y	[71]	CVCL_2196

AML monocytic

Cell line	Sex	Age	Ref	Cellosaurus
ME-1	Male	40Y	[72]	CVCL_2110
MOLM-13	Male	20Y	[73]	CVCL_2119
Mono-Mac-6	Male	64Y	[74]	CVCL_1426
MUTZ-3	Male	29Y	[75]	CVCL_1433
THP-1	Male	1Y	[76]	CVCL_0006
U-937	Male	37Y	[77]	CVCL_0007

AML erythroid

Cell line	Sex	Age	Ref	Cellosaurus
F-36P	Male	68Y	[78]	CVCL_2037
HEL	Male	30Y	[79]	CVCL_0001
OCI-M2	unspecified	56Y	[80]	CVCL_2150
TF-1	Male	35Y	[81]	CVCL_0559

AML megakaryocytic

Cell line	Sex	Age	Ref	Cellosaurus
CMK	Male	10M	[82][83]	CVCL_0216
ELF-153	Male	41Y	[84]	CVCL_2031
M-07e	Female	6M	[85]	CVCL_2106
MEGAL	Female	unspecified	[86]	CVCL_1833
MKPL-1	Male	66Y	[87]	CVCL_2116
UT-7	Male	64Y	[83]	CVCL_2233

CML myeloid BC

Cell line	Sex	Age	Ref	Cellosaurus
EM-2	Female	5Y	[88]	CVCL_1196
K-562	Female	53Y	[89][90]	CVCL_0004
KCL-22	Female	32Y	[91]	CVCL_2091
Ku812	Male	38Y	[92]	CVCL_0379
LAMA-84	Female	29Y	[93]	CVCL_0388
MOLM-20	Female	63Y	[86]	CVCL_2121

CML lymphoid BC

Cell line	Sex	Age	Ref	Cellosaurus
BV-173	Male	45Y	[94]	CVCL_0181
CML-T1	Female	36Y	[95]	CVCL_1126
NALM-1	Female	3Y	[96]	CVCL_0091
TK-6	Male	30Y	[97]	CVCL_X907

MPN

Cell line	Sex	Age	Ref	Cellosaurus
SET-2	Female	71Y	[98]	CVCL_2187

See also

• NCI-60, 60 human cancer cell lines used by the NCI
• List of breast cancer cell lines