LP-44

LP-44 is a drug which acts as a potent and selective agonist at the 5HT₇ serotonin receptor. While LP-44 is less selective than the related compound LP-12, it has been more widely used in research and has been used to show the complex role of 5-HT₇ receptors in several aspects of brain function, including regulation of the sleep-wake cycle and roles in stress, learning and memory.^[1][2][3][4]

LP-44

Identifiers
IUPAC name 4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide
CAS Number	824958-12-5 Y
PubChem CID	11224758
ChemSpider	9399811 N
UNII	M5K3JUP5EZ
CompTox Dashboard (EPA)	DTXSID50459307
Chemical and physical data
Formula	C27H37N3OS
Molar mass	451.67 g·mol−1
3D model (JSmol)	Interactive image
SMILES c3cccc2c3CCCC2NC(=O)CCCCCN(CC4)CCN4c1ccccc1SC
InChI InChI=1S/C27H37N3OS/c1-32-26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31) N Key:JNBBJUHCODFLEG-UHFFFAOYSA-N N
NY (what is this?)  (verify)

See also

• AS-19
• E-55888
• LP-211