Leucine rich repeat containing 3

Leucine rich repeat containing 3 is a protein that in humans is encoded by the LRRC3 gene.^[5]

LRRC3
Identifiers
Aliases	LRRC3, C21orf102, leucine rich repeat containing 3, LRRC3DN, C21orf30
External IDs	OMIM: 617620; MGI: 2447899; HomoloGene: 12789; GeneCards: LRRC3; OMA:LRRC3 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.3 Start 44,455,510 bp[1] End 44,462,196 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 77,733,409 bp[2] End 77,738,370 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver ganglionic eminence muscle layer of sigmoid colon ventricular zone testicle Descending thoracic aorta ascending aorta gastric mucosa apex of heart fundus Top expressed in lumbar spinal ganglion left lobe of liver internal carotid artery external carotid artery urethra supraoptic nucleus right kidney substantia nigra yolk sac proximal tubule More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding protein kinase inhibitor activity Cellular component membrane integral component of membrane cytoplasm Biological process negative regulation of protein kinase activity cytokine-mediated signaling pathway negative regulation of receptor signaling pathway via JAK-STAT Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81543 237387 Ensembl ENSG00000160233 ENSMUSG00000051652 UniProt Q9BY71 P59034 RefSeq (mRNA) NM_030891 NM_145152 RefSeq (protein) NP_112153 NP_660134 Location (UCSC) Chr 21: 44.46 – 44.46 Mb Chr 10: 77.73 – 77.74 Mb PubMed search [3] [4]
Wikidata
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See also

• Leucine rich repeat