LS-115509

LS-115509 is an opioid analgesic related to the 4-phenylpiperidine family. It is comparable to drugs such as prodine and pheneridine, but is distinguished by the presence of an ether group and furan ring at the piperidine 4-position, which are not found in other drugs of this class. In animal studies, it has around 2-3x the potency of morphine depending on what assay is used. Like prodine, it has two stereocenters and four possible enantiomers, but the activity of these has not been tested separately.^[1][2][3]

LS-115509

Clinical data
ATC code	none
Identifiers
IUPAC name 4-ethoxy-4-(furan-2-yl)-3-methyl-1-(2-phenylethyl)piperidine
CAS Number	94876-55-8 Y
PubChem CID	3024404
ChemSpider	2290335
UNII	XG2JQX2JDJ
CompTox Dashboard (EPA)	DTXSID50915236
Chemical and physical data
Formula	C20H27NO2
Molar mass	313.441 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC1(CCN(CC1C)CCC2=CC=CC=C2)C3=CC=CO3
InChI InChI=1S/C20H27NO2/c1-3-23-20(19-10-7-15-22-19)12-14-21(16-17(20)2)13-11-18-8-5-4-6-9-18/h4-10,15,17H,3,11-14,16H2,1-2H3 Key:INLMDDDTZIKNNI-UHFFFAOYSA-N

See also

• PEPAP