LSU rRNA

Large subunit ribosomal ribonucleic acid (LSU rRNA) is the largest of the two major RNA components of the ribosome. Associated with a number of ribosomal proteins, the LSU rRNA forms the large subunit of the ribosome. The LSU rRNA acts as a ribozyme, catalyzing peptide bond formation.

LSU rRNA
Identifiers
Symbol	LSU
Rfam	CL00112
Other data
PDB structures	PDBe

Characteristics

Characteristics of the LSU rRNA for exemplary species.

Type	LSU rRNA size	Species	Length	Accession	Reference
Bacterial (Prokaryotic)	23S	Escherichia coli	2,905 nt	NR_076322.1	[1]
Archaeal (Prokaryotic)	23S	Halobacterium salinarum	2,906 nt	NR_076247.1	[2]
Eukaryotic	5.8S & 28S	Homo sapiens	157 + 5,025 nt	NR_145821.1; M11167.1	[3][4]
Mitochondrial	16S	Homo sapiens	1,559 nt	NC_012920.1	[5][6]
Plastid	23S	Arabidopsis thaliana	2,810 nt	NC_000932.1	[7]

Use in phylogenetics

LSU rRNA sequences are widely used for working out evolutionary relationships among organisms, since they are of ancient origin and are found in all known forms of life.

See also

• SSU rRNA: the small subunit ribosomal ribonucleic acid.