LUF6000

LUF6000 is an experimental drug which acts as a positive allosteric modulator of the adenosine A3 receptor. It has no effect on A3-mediated signalling by itself, but significantly enhances the effect of A3-selective agonists or partial agonists, and can even cause some adenosine A3 antagonists to produce agonist-like signalling. It has antiinflammatory effects in animal studies.^{[1][2][3][4][5][6]}

LUF6000

Identifiers
IUPAC name 2-cyclohexyl-N-(3,4-dichlorophenyl)-3H-imidazo[4,5-c]quinolin-4-amine
CAS Number	890087-21-5
PubChem CID	11711282
IUPHAR/BPS	9446
ChemSpider	9886004
ChEMBL	ChEMBL475346
CompTox Dashboard (EPA)	DTXSID30470994
Chemical and physical data
Formula	C22H20Cl2N4
Molar mass	411.33 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CCC(CC1)C2=NC3=C(N2)C(=NC4=CC=CC=C43)NC5=CC(=C(C=C5)Cl)Cl
InChI InChI=1S/C22H20Cl2N4/c23-16-11-10-14(12-17(16)24)25-22-20-19(15-8-4-5-9-18(15)26-22)27-21(28-20)13-6-2-1-3-7-13/h4-5,8-13H,1-3,6-7H2,(H,25,26)(H,27,28) Key:UWJVRSIGHHSDSJ-UHFFFAOYSA-N