Lacto-usp RNA motif

The Lacto-usp RNA motif is a conserved RNA structure identified in bacteria by bioinformatics.^[1] Lacto-usp RNAs are found exclusively in lactic acid bacteria, and exclusively in the possible 5′ untranslated regions of (5′ UTRs) operons that contain a hypothetical gene and a usp gene. The usp gene encodes the universal stress protein. It was proposed that the Lacto-usp might correspond to the 6S RNA of the relevant species, because four of five of these species lack a predicted 6S RNA, and 6S RNAs commonly occur in 5′ UTRs of usp genes. However, given that the Lacto-usp RNA motif is much shorter than the standard 6S RNA structure, the function of Lacto-usp RNAs remains unclear.

Lacto-usp RNA
Consensus secondary structure of Lacto-usp RNAs
Identifiers
Symbol	Lacto-usp RNA
Rfam	RF01710
Other data
RNA type	sRNA
Domain(s)	Lactic acid bacteria
PDB structures	PDBe