Lelis syndrome

Lelis syndrome is a genetic disorder, a rare condition with dermatological and dental findings^[1] characterized by the association of ectodermal dysplasia (hypotrichosis and hypohidrosis) with acanthosis nigricans. Other clinical features may include palmoplantar hyperkeratosis, nail dystrophy, intellectual deficit,^[2] disturbances of skin pigmentation (perioral and periorbital hyperpigmentation, vitiligo, and perinevic leukoderma)^[2] and hypodontia. Transmission is autosomal recessive.^[1][3]

Lelis syndrome
Other names	Ectodermal dysplasia-acanthosis nigricans syndrome
This condition is inherited in an autosomal recessive manner.
Specialty	Medical genetics

See also

• List of cutaneous conditions