Leonard Herzenberg

Leonard Arthur "Len" Herzenberg (November 5, 1931 – October 27, 2013) was an immunologist, geneticist and professor at Stanford University. His contributions to the development of cell biology made it possible to sort viable cells by their specific properties.^{[2][4][5][6][7][8]}

Leonard Herzenberg
Herzenberg in 2006
Born	Leonard Arthur Herzenberg (1931-11-05)November 5, 1931 New York City, US
Died	October 27, 2013(2013-10-27) (aged 81) Stanford, California, US
Alma mater	Brooklyn College California Institute of Technology
Known for	Flow cytometry (FACS)[1]
Spouse	Leonore Herzenberg[2]
Children	4, including Jana
Awards	Kyoto Prize (2006)
Scientific career
Fields	Immunology, genetics
Institutions	Stanford University Pasteur Institute
Thesis	Studies on a Cytochrome Destroying System in Neurospora (1956)
Doctoral advisor	Herschel K. Mitchell[3]

Education

Herzenberg was born in New York City, on November 5, 1931. He received his bachelor's degree in 1952 from Brooklyn College in biology and chemistry. In 1955, he received his Ph.D. from California Institute of Technology in biochemistry with a specialization in immunology for studies on cytochrome in Neurospora.^[3]

Career

After school he was a postdoctoral fellow at the American Cancer Society, working in France at the Pasteur Institute. He returned to the United States in 1957 and worked for the National Institutes of Health as an officer in the Public Health Service department. He started working at Stanford in 1959. He eventually earned the title Professor of Genetics.^[7]

In 1970 Herzenberg developed the fluorescence-activated cell sorter^[1][7] which revolutionized immunology and cancer biology, and is the basis for purification of adult stem cells.

During a sabbatical in the laboratory of Cesar Milstein between 1976 and 1977, Herzenberg coined the term hybridoma for hybrid cells that result from the fusion of B cells and myeloma cells.^[9]

Personal life

Herzenberg and his wife, Leonore Herzenberg,^[2] ran the Herzenberg Laboratory at Stanford together^[10] until his death. Their daughter, Jana Herzen, is a singer-songwriter and the founder of Motéma Music. He died on October 27, 2013, aged 81.^[6]

Awards and honours

Herzenberg received a range of honours and awards during his life including:

• 1998 American Association of Immunologists Lifetime Achievement Award^[11]
• 2002 Edwin F. Ullman Award, American Association of Clinical Chemistry
• 2004 Special Novartis Prize for Immunology (the only winner of this award)
• 2005 Abbott Laboratories Award in Clinical and Diagnostic Immunology, American Society for Microbiology
• 2006 Kyoto award for his work in cell biology;
• 2007 Ceppellini Award, International Foundation for Research in Experimental Medicine, with his wife Lee Herzenberg for "their internationally recognized contributions to medicine"
• 2013 ABRF Annual Award for Outstanding Contributions to Biomolecular Technologies