Levopimaradiene synthase

Levopimaradiene synthase (EC 4.2.3.32, PtTPS-LAS, LPS, copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]) is an enzyme with systematic name (+)-copalyl-diphosphate diphosphate-lyase (abieta-8(14),12-diene-forming).^[1][2] This enzyme catalyses the following chemical reaction

(+)-copalyl diphosphate ${\displaystyle \rightleftharpoons }$ abieta-8(14),12-diene + diphosphate

Levopimaradiene synthase
Identifiers
EC no.	4.2.3.32
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides.