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Lipophosphoglycan

Eukaryotic cell surface macromolecule From Wikipedia, the free encyclopedia

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Lipophosphoglycan (LPG) is a class of molecules found on the surface of some eukaryotes, in particular protozoa. Each is made up of two parts, lipid and polysaccharide (also called glycan). They are bonded by a phosphodiester, hence the name lipo-phospho-glycan.[1]

One species with extensive lipophosphoglycan coating is Leishmania, a group of single-celled protozoan parasite which cause leishmaniasis in many mammals, including humans. Their coats help modulate their hosts' immunological responses.[2] LPG-like substances are released into medium by the parasite and are called excreted factor in aggregate.[2]

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