Lisch epithelial corneal dystrophy

Lisch epithelial corneal dystrophy (LECD), also known as band-shaped and whorled microcystic dystrophy of the corneal epithelium, is a rare form of corneal dystrophy first described in 1992 by Lisch et al.^[1] In one study it was linked to chromosomal region Xp22.3, with as yet unknown candidate genes.^[2]

Lisch epithelial corneal dystrophy
Other names	Band-shaped and whorled microcystic dystrophy of the corneal epithelium
X-linked recessive is the inheritance pattern of this condition
Specialty	Ophthalmology

The main features of this disease are bilateral or unilateral gray band-shaped and feathery opacities. They sometimes take on a form of a whirlpool, repeating the known pattern of corneal epithelium renewal. Abrasion of the epithelium in 3 patients brought only temporary relief, with abnormal epithelium regrowth in several months.^{[citation needed]}

Epithelial cells in the zones of opacity were shown to have diffuse cytoplasmic vacuoles with as yet unestablished content.^{[citation needed]}