| Laboratory Name | Government Organization[3][4][5] |
| Ames National Laboratory | United States Department of Energy |
| ARPA-E | United States Department of Energy |
| Oak Ridge National Laboratory | United States Department of Energy |
| Brookhaven National Laboratory | United States Department of Energy |
| SLAC National Accelerator Laboratory | United States Department of Energy |
| Office of Science | United States Department of Energy |
| Pacific Northwest National Laboratory | United States Department of Energy |
| Fermi National Accelerator Laboratory | United States Department of Energy |
| Idaho National Laboratory | United States Department of Energy |
| National Renewable Energy Laboratory | United States Department of Energy |
| Lawrence Livermore National Laboratory | United States Department of Energy |
| Los Alamos National Laboratory | United States Department of Energy |
| National Energy Technology Laboratory | United States Department of Energy |
| Sandia National Laboratories | United States Department of Energy |
| Savannah River National Laboratory | United States Department of Energy |
| Thomas Jefferson National Accelerator Facility | United States Department of Energy |
| Armstrong Flight Research Center | NASA |
| Glenn Research Center | NASA |
| Goddard Space Flight Center | NASA |
| Johnson Space Center | NASA |
| Langley Research Center | NASA |
| Marshall Space Flight Center | NASA |
| Ames Research Center | NASA |
| Space Radiation Laboratory | NASA |
| Stennis Space Center | NASA |
| Air Force Research Laboratory | United States Air Force |
| Air Force Systems Command | United States Air Force |
| Area 51 | United States Air Force |
| Army Research Laboratory | United States Army |
| Army Combat Capabilities Development Command | United States Army |
| Army Medical Research and Development Command | United States Army |
| Engineer Research and Development Center | United States Army Corps of Engineers |
| United States Marine Corps Warfighting Laboratory | United States Marine Corps |
| Office of Naval Research | United States Navy |
| Naval Research Laboratory | United States Navy |
| United States Coast Guard Research & Development Center | United States Coast Guard |
| The Aerospace Corporation | United States Department of Defense |
| DARPA | United States Department of Defense |
| Center for Communications and Computing | Institute for Defense Analyses |
| National Biodefense Analysis and Countermeasures Center | Department of Homeland Security |
| National Cybersecurity FFRDC | Department of Homeland Security |
| DHS Science and Technology Directorate | Department of Homeland Security |
| Intelligence Advanced Research Projects Activity | Office of the Director of National Intelligence |
| Frederick National Laboratory for Cancer Research | National Cancer Institute |
| National Center for Atmospheric Research | University Corporation for Atmospheric Research |
| Marine Biological Laboratory | National Science Foundation |
| National Optical-Infrared Astronomy Research Laboratory | National Science Foundation |
| National Solar Observatory | National Science Foundation |
| National Institutes of Health | Department of Health and Human Services |
| Advanced Research Projects Agency for Health (ARPA-H) | Department of Health and Human Services |
| United States Geological Survey | Department of the Interior |
| National Institute of Justice | Department of Justice |
| Research and Innovative Technology Administration | United States Department of Transportation |
| Long-Term Pavement Performance | Federal Highway Administration |
| National Oceanic and Atmospheric Administration (NOAA) | United States Department of Commerce |
| Veterans Health Administration Office of Research and Development | Department of Veterans Affairs |
| Federal Judicial Center | Federal judiciary of the United States |
| Agricultural Research Service | United States Department of Agriculture |
| National Institute of Food and Agriculture | United States Department of Agriculture |
| Economic Research Service | United States Department of Agriculture |
| Forest Products Laboratory | United States Forest Service |
| Electronics and Telecommunications Research Institute | Daedeok Science Town (South Korea) |
| Central Mechanical Engineering Research Institute | Council of Scientific and Industrial Research (India) |
| Max Planck Institute for Intelligent Systems | Max Planck Society (Germany) |
| Vector Institute | Canadian Institute for Advanced Research |
| National Institute for Materials Science | National Research and Development Agency (Japan) |
| RIKEN | National Research and Development Agency (Japan) |
| National Institute of Advanced Industrial Science and Technology | National Research and Development Agency (Japan) |
| Japan Aerospace Exploration Agency | National Research and Development Agency (Japan) |
| National Institute of Genetics | National Research and Development Agency (Japan) |
| National Institute for Basic Biology | National Research and Development Agency (Japan) |
| National Institute of Informatics | National Research and Development Agency (Japan) |
| National Cancer Center | National Research and Development Agency (Japan) |
| National Institute of Information and Communications Technology | National Research and Development Agency (Japan) |
| National Institute of Infectious Diseases | National Research and Development Agency (Japan) |
| European Space Research Organisation | European Space Agency |
| Central Laser Facility | Rutherford Appleton Laboratory |
| Diamond Light Source | Rutherford Appleton Laboratory |
| ISIS Neutron and Muon Source | Rutherford Appleton Laboratory |
| CERN | Science and Technology Facilities Council |
| DiRAC | Science and Technology Facilities Council |
| European Synchrotron Radiation Facility | Science and Technology Facilities Council |
| Institut Laue-Langevin | Science and Technology Facilities Council |
| UK Astronomy Technology Centre | Science and Technology Facilities Council |
| Hartree Centre | Science and Technology Facilities Council |
| ALICE, EMMA, CLARA | Daresbury Laboratory |
| Worldwide LHC Computing Grid | GridPP |
| Boulby Mine underground laboratory | Science and Technology Facilities Council |
| Laser Interferometer Gravitational-Wave Observatory | NSF / STFC |