| Year |
Category |
Nominee(s) / Episode |
Result |
| 2003 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Won |
| Outstanding Main Title Theme Music | Jeff Beal | Won |
| 2004 | Outstanding Lead Actor – Comedy Series | Tony Shalhoub | Nominated |
| Outstanding Casting – Comedy Series | | Nominated |
| Outstanding Guest Actor in a Comedy Series | John Turturro / "Mr. Monk and the Three Pies" | Won |
| Outstanding Main Title Theme Music | Randy Newman | Won |
| 2005 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Won |
| Outstanding Directing for a Comedy Series | Randall Zisk / "Mr. Monk Takes His Medicine" | Nominated |
| 2006 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Won |
| Outstanding Guest Actress in a Comedy Series | Laurie Metcalf / "Mr. Monk Bumps His Head" | Nominated |
| 2007 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Nominated |
| Outstanding Guest Actor – Comedy Series | Stanley Tucci / "Mr. Monk and the Actor" | Won |
| 2008 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Nominated |
| Outstanding Guest Actress – Comedy Series | Sarah Silverman / "Mr. Monk and His Biggest Fan" | Nominated |
| 2009 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub | Nominated |
| Outstanding Guest Actress in a Comedy Series | Gena Rowlands / "Mr. Monk and the Lady Next Door" | Nominated |
| 2010 | Outstanding Lead Actor in a Comedy Series | Tony Shalhoub[2] / "Mr. Monk and the End" | Nominated |
| Outstanding Original Music And Lyrics | Randy Newman[2] for "When I'm Gone" / "Mr. Monk and the End (Part Two)" | Won |