| Video Game |
Year |
Description |
| Amnesia: The Dark Descent & Amnesia: A Machine for Pigs | 2010 & 2013 | The gatherer enemies are deformed human-like monsters; their eyelids are cut off and their bottom jaw is mutilated and stretched down and attached to their chests leaving their mouths permanently open. |
| BioShock series | 2007–2014 | Both BioShock and BioShock 2 consist of enemies called Splicers, who were once normal humans that were heavily mutated and driven insane from a drug called ADAM, which they used to re-write their genetic codes to develop "psychic" powers such as telekinesis and pyrokinesis. The game also contains the iconic Big Daddy, which is a man whose skin has been removed, and whose organs have been grafted to the inside of a modified deep-sea diving suit. BioShock Infinite uses a similar premise, although in this case series of compounds called Vigors grant the player extraordinary abilities; however, unlike ADAM they are consumed orally rather than injected. In this game, the Big Daddy has been replaced by the Handyman, a human whose spinal cord, head, and heart have been connected to a steampunk robotic frame with minor effects like psychological trauma. |
| Bloodborne | 2015 | |
| Corpse Party series | 1996–2021 | |
| Dead Space series | 2008–present | The primary enemies of the series are called Necromorphs, which are mutated humans with protruding appendages, open wounds, and rotting flesh. |
| Fallout series | 1997–present | The fallout games take place in a post-apocalyptic wasteland, and as such, many of the enemies and species have physical deformities from the radiation. |
| Half-Life series | 1998–2007 | Parasitic monsters known as Headcrabs attach themselves to heads of people and cause them to develop mutations such as elongated claws and gaping jaws in their chests. |
| Inside | 2016 | An indie puzzle platformer developed by Playdead. Inside tells the story about a young boy as he struggles against evil forces trying to take over the world. The boy infiltrates a massive facility where scientists perform mind-control and underwater experiments on human bodies. |
| Lisa: The Painful | 2014 | |
| The Last of Us Part II | 2020 |
An action adventure/survival horror game set in a post apocalyptic world ravaged by a mutated fungus, transforming humans into hostile creatures with horrific body disfigurements. One such specimen consists of several infected humans fused together by the fungus called the Rat King. |
| Outlast | 2013 | A first-person survival horror game in which an investigative journalist explores an asylum housing inmates displaying various degrees of bodily mutilation and/or mutation. |
| Parasite Eve series | 1998–2010 | The Squaresoft (now known as Square Enix) video game based on the 1996 Japanese SF horror novel of the same title, was released in 1998. The premise of both the novel and "cinematic RPG" being that the mitochondria, organelles from early aerobic bacteria that formed a symbiotic partnership with cells of most present-day multicellular eukaryotes, e.g. humans, are able to retain their separate identity as independent organisms in the form of cellular parasites. A dispersed intelligence, known as Eve, was able to take over the consciousness of certain individuals to make them reproduce and form an ultimate organism that will bring the downfall of humanity and other creatures alike. She can also turn organisms into monstrous beings. |
| Resident Evil series | 1996–present | A pharmaceutical company uses a mutagenic T-Virus in order to produce monsters to sell as weapons. The most basic were zombie versions of whatever organism was infected or giant versions of insects. There are also human/insect and human/reptilian hybrids, malformed super-soldiers called "Tyrants", and various other mutants. Later games introduce, for example, more viruses, parasites like Las Plagas (an ancient parasite which take over nervous systems), and a superfungus called a Mold. |
| Scorn | 2022 | A first-person biopunk survival horror adventure game developed by Ebb Software. |
| Soma | 2015 | A SF survival horror game developed by Frictional Games. |
| Still Wakes the Deep |
2024 |
A narrative psychological horror game developed by The Chinese Room and published by Secret Mode. |
| Struggling | 2020 | In this game, the player controls Troy, a fleshy creature that resembles two cojoined heads with a pair of long arms, which are used to drag through levels. During the game the player faces other similarly bizarre creatures known as "abomination gods" which serve as the main bosses of the game. The game as a whole has a body horror theme but it goes with a more comical approach and has an atypical cartoon art style. |
| The Thing | 2002 | A sequel to the 1982 film The Thing, player follows Captain Blake, a member of a U.S. Special Forces team sent to the Antarctic outpost featured in the film to determine what has happened to the research crew. The enemies encountered come in three main forms. "Scuttlers" are small Things formed from the limbs and appendages of infected personnel. "Walkers" are larger and much stronger than Scuttlers, and finally the Bosses are larger and much more powerful than Walkers. |
| Zoochosis | 2024 | An upcoming first-person survival horror indie game in which the player assumes the role of a zookeeper tasked with creating vaccines and curing mutated animals. |
