List of largest biomedical companies by market capitalization

The following is a list of independent pharmaceutical, biotechnology and medical companies listed on a stock exchange (as indicated) with current market capitalization of at least US$10 billion, ranked by their market capitalization.

It does not include biotechnology companies that are currently owned by, or form a part of, larger pharmaceutical groups.

Ranking by market capitalization

The following table lists the largest biotechnology and pharmaceutical companies ranked by market capitalization in billion US dollars. The change column indicates the company's relative position in this list compared to their relative position in the preceding year; i.e., an increase would be moving closer to rank 1 and vice versa.

Largest biotechnology and pharmaceutical companies ranked by market capitalization in billion US dollars.

Rank	Chg	Company	Country	Traded on	Largest	2020[1]	2019	2018	2017	2016[2][3]	2015[4]	2014[5]	2013
1		Johnson & Johnson[P]	USA	NYSE: JNJ	399.9 (Dec 2020)	399.99	385.0	346.1	375.4	314.1	284.2	277.8	258.3
2	1	Roche[P]	SUI	SIX: ROG	291.1 (Dec 2020)	291.12	281.1	209.3	216.7	192.1	234.7	258.5	240.3
3	2	Pfizer[P]	USA	NYSE: PFE	310.5 (Jul 2000)	208.11	216.7	259.7	215.9	196.3	199.3	205.4	196.0
4	1	Novartis[P]	SUI	NYSE: NVS	275.2 (Jul 2015)	202.09	240.0	200.0	196.7	170.5	206.1	229.8	195.0
5	1	Merck & Co.[P]	USA	NYSE: MRK	232.9 (Dec 2019)	201.80	232.9	205.8	153.3	164.3	147.6	166.9	146.5
6		Moderna[P]	USA	NSE: MRNA	201 (Sep 2021)	68.5	45.0						-
7		Abbott Laboratories[P]	USA	NYSE: ABT	190.4 (Dec 2020)	190.44	153.5	126.8	99.3	56.4	67.0	67.9	59.3
8	2	AbbVie[B]	USA	NYSE: ABBV	196.2 (Jan 2018)	182.27	130.9	146.3	154.4	100.2	96.8	104.1	83.8
9		Novo Nordisk[P]	DEN	NYSE: NVO	161.9 (Dec 2020)	161.99	137.1	111.9	131.2	92.6	153.9	125.4	-
10	2	Eli Lilly & Co[P]	USA	NYSE: LLY	158.3 (Dec 2020)	158.30	126.9	125.6	93.0	80.9	93.4	76.6	57.0
11	3	Bristol-Myers Squibb[P]	USA	Nasdaq: BMY	137.8 (Dec 2020)	137.85	105.0	85.0	100.3	98.2	114.8	97.6	87.2
12	4	Amgen[B]	USA	Nasdaq: AMGN	145.8 (Dec 2019)	129.79	144.6	128.8	126.2	108.9	122.5	93.1	78.7
13	2	AstraZeneca[P]	GBR  SWE	LSE: AZN	130.8 (Dec 2019)	129.44	130.8	96.2	87.9	68.8	85.8	88.9	74.6
14	4	Sanofi[P]	FRA	NYSE: SNY	151.3 (Sep 2014)	120.66	63.5	108.4	108.2	101.8	111.8	138.1	142.0
15	2	GlaxoSmithKline[P]	GBR	LSE: GSK	174.9 (May 2006)	90.15	117.2	94.8	87.9	93.3	97.6	128.9	129.6
16	1	Stryker Corporation[P]	USA	NYSE: SYK	88.8 (Dec 2020)	88.81	78.5	58.6	58.0	45.1	34.7	35.7	28.4
17	2	Zoetis[P]	USA	Nasdaq: ZTS	76.6 (Aug 2020)	75.97	63.2	41.4	35.1	26.4	23.8	21.6	16.3
18	3	Gilead Sciences[B]	USA	Nasdaq: GILD	179.6 (Jun 2013)	71.93	82.3	81.6	93.6	96.6	145.8	109.0	78.4
19	6	Daiichi Sankyo[P]	JPN	Nasdaq: DSNKY	45.3 (Dec 2019)	63.92	45.3	22.7	27.5	35.3	38.8	33.2	28.7
20	1	Vertex Pharmaceuticals[B]	USA	Nasdaq: VRTX	78.9 (Jul 2020)	61.33	56.3	42.2	37.9	18.3	31.0	28.7	17.4
21	4	Bayer[P]	GER	FWB: BAYN	129.0 (Mar 2015)	58.12	80.1	63.1	101.9	85.3	103.2	113.2	117.4
22	2	Takeda Pharmaceutical[P]	JPN	Nasdaq: TAK	61.5 (Dec 2019)	56.78	61.5	52.9	40.2	45.6	47.8	37.5	34.3
23	1	Illumina[B]	USA	Nasdaq: ILMN	56.0 (Jul 2019)	53.51	48.2	44.1	40.2	39.4	35.4	28.6	25.7
24	2	Regeneron Pharmaceuticals[B]	USA	Nasdaq: REGN	61.4 (Aug 2015)	52.52	41.2	40.3	40.4	39.3	56.5	42.0	27.4
25	3	Biogen[B]	USA	Nasdaq: BIIB	111.7 (Mar 2015)	38.66	54.7	63.5	67.4	61.6	68.3	79.7	66.1
26	2	Alexion Pharmaceuticals[P]	USA	Nasdaq: ALXN	47.0 (Jul 2015)	33.52	24.3	21.7	26.7	27.4	43.1	36.7	26.0
27	3	Seagen[B]	USA	Nasdaq: SGEN	38.2 (Oct 2020)	34.44	19.5	13.8
28	1	Astellas[P]	JPN	TYO: 4503	40.6 (Dec 2015)	27.52	32.7	23.8	29.3	25.7	40.6	35.8	27.6
29	4	Genmab[B]	DEN	Nasdaq: GMAB	25.9 (Nov 2020)	25.53	14.5	10.6	10.8	10.8	8.8	3.8	2.6
30	1	Eisai Pharmaceutical[P]	JPN	TYO: 4523	37.3 (Dec 2016)	19.93	21.5	23.0	24.5	37.3	28.8	30.2	28.7
31		Alnylam Pharmaceuticals [P]	USA	NSE: ALNY[6]	23.36	18.5	24.0	21.0	16.0				-
32		Incyte[P]	USA	NSE: INCY	31.2 (Mar 2017)	19.25	18.8	13.5	18.3	15.4	10.6	7.3	4.6
33		BioMarin[P]	USA	NSE: BMRN	24.0 (Jul 2015)	16.03	15.2	15.1	18.3	20.4	13.8	12.9	10.8
34		BeiGene [P]	CHN	SSE: 688235	33.14 (Nov 2021)	34.20	27.00	26.00	24.03	10.28	8.33	4.45	1.20
35	1	BioNTech[P]	GER	NSE: BNTX	44.07	62.52	19.62	7.68					-
36	1	Horizon Therapeutics[P]	USA	NSE: HZNP	18.06 (Dec 2020)	14.2	11.6	9.3	5.0	6.5	2.8	2.0	-
37	1	10x Genomics[7][P]	USA	NSE: TXG	17.54	11.2							-
38	1	Jiangsu Hengrui Medicine[P]	CHN	SSE: 600276	41.17	59.98	93.42	60.85	30.53	30.54	16.79	15.10	-
39	1	Elanco[P]	USA	NYSE: ELAN	13.06 (Nov 2020)	11.2							-
40	1	Celltrion[P]	ROK	KRX: 068270	23.03 (2021)	40.90	19.22						-
41	1	Viatris[P]	USA	NSE: VTRS	18.50 (Dec 2021)								-
42	1	Sun Pharma[P]	IND	NSE: SUNPHARMA	27.15 (2021)	19.01							-
43	1	Divi's Laboratories[P]	IND	NSE: DIVISLAB	15.29 (Nov 2021)								-
44	1	Dr. Reddy's Laboratories[P]	IND	NSE: DRREDDY	10.94 (2021)	11.75							-
45	1	Cipla[P]	IND	NSE: CIPLA	10.21 (Dec 2021)	10.19							-

• ^B – Biotechnology company
• ^P – Pharmaceutical company

See also

• List of largest biomedical companies by revenue