M7GpppX diphosphatase

M7GpppX diphosphatase (EC 3.6.1.59, DcpS, m7GpppX pyrophosphatase, m7GpppN m7GMP phosphohydrolase) is an enzyme with systematic name m⁷G⁵'ppp5'N m⁷GMP phosphohydrolase.^{[1][2][3][4][5]} This enzyme catalyses the following chemical reaction

(1) m⁷G⁵'ppp5'N(3'ppp5'N)_n + H₂O ${\displaystyle \rightleftharpoons }$ 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)_n

(2) 7-methylguanosine 5'-diphosphate + H₂O ${\displaystyle \rightleftharpoons }$ 7-methylguanosine 5'-phosphate + phosphate

M7GpppX diphosphatase
Identifiers
EC no.	3.6.1.59
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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Decapping is a process in the control of eukaryotic mRNA degradation.