MADAM-6

MADAM-6, or 2,N-dimethyl-4,5-methylenedioxyamphetamine or as 6-methyl-MDMA, is a drug of the phenethylamine, amphetamine, and MDxx families, similar in structure to MDMA (ecstasy).^[2] MADAM-6 was first synthesized by Alexander Shulgin.^[1] In Shulgin's book PiHKAL, the minimum dosage is listed as greater than 280 mg, and the duration is unknown.^[1] MADAM-6 produces few to no effects and Shulgin describes it as "not active".^[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of MADAM-6.

MADAM-6

Clinical data
Other names	6-Methyl-MDMA; 2,N-Dimethyl-4,5-methylenedioxyamphetamine
Routes of administration	Oral[1]
ATC code	None
Pharmacokinetic data
Duration of action	Unknown[1]
Identifiers
IUPAC name N-methyl-1-(6-methyl-2H-1,3-benzodioxol-5-yl)propan-2-amine
CAS Number	207740-46-3
PubChem CID	44719578
ChemSpider	21106340
UNII	W3H6GHJ73C
CompTox Dashboard (EPA)	DTXSID80660368
Chemical and physical data
Formula	C12H17NO2
Molar mass	207.273 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1(=CC2=C(C=C1CC(C)NC)OCO2)C
InChI InChI=1S/C12H17NO2/c1-8-4-11-12(15-7-14-11)6-10(8)5-9(2)13-3/h4,6,9,13H,5,7H2,1-3H3 Key:CRQPDNIUPWXPNK-UHFFFAOYSA-N

MADAM-6 has been studied for its potential antiparkinsonian effects.^[3] However, no clinical trials suggest the drug is effective against Parkinson's disease.

See also

• Substituted methylenedioxyphenethylamine