MADAM-6

MADAM-6, or 2, N-dimethyl-4,5-methylenedioxyamphetamine, is a lesser-known recreational drug of the methamphetamine class, similar in structure to MDMA (ecstasy).^[1] MADAM-6 was first synthesized by Alexander Shulgin.^[2] In Shulgin's book PiHKAL, the minimum dosage is listed as greater than 280 mg, and the duration is unknown.^[2] MADAM-6 produces few to no effects and Shulgin describes it as "not active".^[2] Very little data exists about the pharmacological properties, metabolism, and toxicity of MADAM-6.

MADAM-6

Names
Preferred IUPAC name N-Methyl-1-(6-methyl-2H-1,3-benzodioxol-5-yl)propan-2-amine
Other names 6-Methyl-MDMA
Identifiers
CAS Number	207740-46-3
3D model (JSmol)	Interactive image
ChemSpider	21106340
PubChem CID	44719578
UNII	W3H6GHJ73C
CompTox Dashboard (EPA)	DTXSID80660368
InChI InChI=1S/C12H17NO2/c1-8-4-11-12(15-7-14-11)6-10(8)5-9(2)13-3/h4,6,9,13H,5,7H2,1-3H3 Key: CRQPDNIUPWXPNK-UHFFFAOYSA-N
SMILES C1(=CC2=C(C=C1CC(C)NC)OCO2)C
Properties
Chemical formula	C12H17NO2
Molar mass	207.273 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

MADAM-6 has been studied for its potential antiparkinsonian effects.^[3] However, no clinical trials suggest the drug is effective against Parkinson's disease.

See also

• Phenethylamine
• Psychedelics, dissociatives and deliriants