3',4'-Methylenedioxy-α-pyrrolidinobutiophenone

3',4'-Methylenedioxy-α-pyrrolidinobutiophenone
Legal status
Legal status	CA: Schedule I; DE: NpSG (Industrial and scientific use only); UK: Class B; Illegal in China and Poland;
Identifiers
	IUPAC name 1-(2H-1,3-Benzodioxol-5-yl)-2-(pyrrolidin-1-yl)butan-1-one;
CAS Number	784985-33-7;
PubChem CID	71300672;
ChemSpider	52084589;
UNII	979L917V7T;
ChEBI	CHEBI:234466;
CompTox Dashboard (EPA)	DTXSID101024630 ;
Chemical and physical data
Formula	C15H19NO3
Molar mass	261.321 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3;
	InChI InChI=1S/C15H19NO3/c1-2-12(16-7-3-4-8-16)15(17)11-5-6-13-14(9-11)19-10-18-13/h5-6,9,12H,2-4,7-8,10H2,1H3; Key:OLVLMDVPMCIBQW-UHFFFAOYSA-N;

3',4'-Methylenedioxy-α-pyrrolidinobutyrophenone (MDPBP) is a stimulant of the cathinone class developed in the 1960s,^[1]^[2] which has been reported as a novel designer drug.^[3]^[4] MDPBP is sometimes sold under the name "NRG-1" as a mixture with other cathinone derivatives, including flephedrone, pentylone, MαPPP and its higher homologue MDPV.^[5] As with other cathinones, MDPBP has been shown to have reinforcing effects in rats.^[6]

Quick Facts Legal status, Identifiers ...

The main metabolic steps are thought to be demethylenation followed by methylation of one hydroxy group, aromatic and side chain hydroxylation, oxidation of the pyrrolidine ring to the corresponding lactam as well as ring opening to the corresponding carboxylic acid. CYP2C19 and CYP2D6 have been identified as the isoenzymes mainly responsible for demethylenation.^[7]

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3',4'-Methylenedioxy-α-pyrrolidinobutiophenone

Legal Status

See also

References

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