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MOTS-c
Peptide encoded in mitochondrial DNA From Wikipedia, the free encyclopedia
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MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a peptide encoded in mitochondrial DNA. It is believed to be involved in skeletal muscle and glucose metabolism. It is upregulated in response to exercise, and is considered an exercise mimetic.[1][2]
MOTS-c binds to casein kinase 2.[3]
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Researchers discovered MOTS-c in 2015.[4]
MOTS-c is not approved to treat any medical condition and is banned by the World Anti-Doping Agency, explicitly beginning in 2024.[5]
References
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