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Mitochondrial ribosomal protein L30

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Mitochondrial ribosomal protein L30
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39S ribosomal protein L30, mitochondrial is a protein that in humans is encoded by the MRPL30 gene.[5]

Quick Facts MRPL30, Available structures ...
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Function

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified at least two transcript variants encoding the same protein. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p.[5]

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References

Further reading

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