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Mafosfamide

Chemical compound From Wikipedia, the free encyclopedia

Mafosfamide
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Mafosfamide (INN) is an oxazaphosphorine (cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. It is metabolized by cytochrome P450 into 4-hydroxycyclophosphamide, which is then converted into aldophosphamide, which, in turn yields the cytotoxic metabolites phosphoramide mustard and acrolein.[1]

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Several Phase I trials have been completed.[2][3]

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