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Maleamic acid
Chemical compound From Wikipedia, the free encyclopedia
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Maleamic acid is an organic compound with the formula HO2CCH=CHC(O)NH2. It is the amide formed by reaction of maleic anhydride with ammonia. It is a colorless solid.[1] Maleamic acid is the product of the action of the enzyme maleimide hydrolase.
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Related compounds
A variety of maleamic acids are known. Commonly they are prepared by the reaction of an amine with maleic anhydride.[2]
Aside from maleic anhydride, other common cyclic anhydrides (and imides) undergo ring-opening to give amido carboxylic acids. Succinic anhydride gives succinamic acid (HO2CCH2CH2C(O)NH2), citraconic anhydride gives two isomers of citraconamic acid (HO2CCH2CH(CH3)C(O)NH2 and HO2CCH(CH3)CH2C(O)NH2), and phthalimide gives phthalamidic acid (HO2CC6H4C(O)NH2).[3]
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References
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