Manchester score

Manchester score is an indicator of prognosis in small cell lung cancer.^[1][2] It is calculated from a number of physical and biochemical markers.

A patient with small cell lung cancer scores one point for each of the following: ^{[citation needed]}-

• Serum lactate dehydrogenase exceeds the upper limit of the reference range.
• Serum sodium concentration less than 132 mmol/L.
• Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
• Serum bicarbonate less than 24.
• Karnofsky performance status less than 60.
• Extensive stage disease.

Prognosis

Prognosis of small cell lung cancer according to Manchester score^[3]

Manchester score	Prognostic group	Two year survival (%)
0-1	Good	16.2
2-3	Medium	2.5
4 or more	Poor	0