Mazaticol

Mazaticol (Pentona) is an anticholinergic used as an antiparkinsonian agent in Japan.

Mazaticol

Clinical data
Routes of administration	Oral
ATC code	N04AA10 (WHO)
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name [(1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(di-2-thienyl)acetate
CAS Number	42024-98-6
PubChem CID	68667
ChemSpider	61921
UNII	I6X824OGWZ
CompTox Dashboard (EPA)	DTXSID1057743
Chemical and physical data
Formula	C21H27NO3S2
Molar mass	405.57 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1(CC[C@@H]2C[C@H](C[C@H]1N2C)OC(=O)C(c3cccs3)(c4cccs4)O)C
InChI InChI=1S/C21H27NO3S2/c1-20(2)9-8-14-12-15(13-16(20)22(14)3)25-19(23)21(24,17-6-4-10-26-17)18-7-5-11-27-18/h4-7,10-11,14-16,24H,8-9,12-13H2,1-3H3/t14-,15-,16-/m1/s1 Key:AMHPTVWBZSYFSS-BZUAXINKSA-N
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The compound was known as PG-501 is first mentioned in Japanese studies in the early 1970s, noting "PG-501 was found to have pronounced anti-acetylcholine, anti-tremorine-induced tremor, anti-physostigmine-induced death, anti-haloperidol-induced parkinsonism and anti EEG arousal activities."^[1][2]