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Methylecgonone reductase

From Wikipedia, the free encyclopedia

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Methylecgonone reductase (EC 1.1.1.334, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

ecgonine methyl ester + NADP+ ecgonone methyl ester + NADPH + H+

The enzyme from the plant Erythroxylum coca participates in the biosynthesis of cocaine.

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