Methylobacterium mesophilicum

Methylobacterium mesophilicum is a Gram-negative, soil-dwelling bacterium, reported to be an opportunistic pathogen in immunocomprimised patients.

Methylobacterium mesophilicum
Scientific classification
Domain:	Bacteria
Kingdom:	Pseudomonadati
Phylum:	Pseudomonadota
Class:	Alphaproteobacteria
Order:	Hyphomicrobiales
Family:	Methylobacteriaceae
Genus:	Methylobacterium
Species:	M. mesophilicum
Binomial name
Methylobacterium mesophilicum (Austin and Goodfellow 1979) Green and Bousfield 1983
Synonyms
Pseudomonas mesophilica Austin and Goodfellow 1979

Methylobacteria are typically slow-growing and produce pink-pigmented colonies. Pink pigmentation is the primary diagnostic characteristic used in the initial isolation of Methylobacteria. With extended incubation, pink colonies often take on a coral hue. M. mesophilicum and M. zatmanii are the two most commonly reported species isolated in clinical samples.^[1][2]

Methylobacteria have been reported to exhibit resistance to chlorination^[3] and have been isolated from tap water in various clinical settings including: an investigation of a pseudo-outbreak,^[4] water from dental units,^[5] and blood purification units.^{[citation needed]} Tap water is a suspected mode of transmission. The presence of these organisms in tap water prompted suggestions that it may be helpful to monitor these organisms in water distribution systems in hospital units for immunocompromised patients.^[1]