Midaflur

Midaflur (INN; EXP 338) is an extremely stable 3-imidazoline derivative with central skeletal muscle relaxant and sedative properties in humans^[1] and other species of mammals, exhibiting consistently high oral bioavailability and a long duration of action. While its pharmacodynamics remain poorly understood, midaflur resembles meprobamate and pentobarbital in terms of observed effects while being considerably more potent.^[2]

Midaflur

Clinical data
ATC code	None
Identifiers
IUPAC name 2,2,5,5-Tetrakis(trifluoromethyl)-2,5-dihydro-1H-imidazol-4-amine
CAS Number	23757-42-8
PubChem CID	32068
ChemSpider	29737
UNII	840CTL676L
KEGG	D05027
ChEMBL	ChEMBL2104707
CompTox Dashboard (EPA)	DTXSID50178425
Chemical and physical data
Formula	C7H3F12N3
Molar mass	357.103 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1(=NC(NC1(C(F)(F)F)C(F)(F)F)(C(F)(F)F)C(F)(F)F)N
InChI InChI=1S/C7H3F12N3/c8-4(9,10)2(5(11,12)13)1(20)21-3(22-2,6(14,15)16)7(17,18)19/h22H,(H2,20,21) Key:KYWMWUUMCDZISK-UHFFFAOYSA-N

See also

• Propofol
• Pentobarbital