Mir-101 microRNA precursor family

miR-101 microRNA precursor is a small non-coding RNA that regulates gene expression. Expression of miR-101 has been validated in both human (MI0000103, MI0000739)^[1] and mouse (MI0000148).^[2] This microRNA appears to be specific to the vertebrates and has now been predicted or confirmed in a wide range of vertebrate species (MIPF0000046). The precursor microRNA is a stem-loop structure of about 70 nucleotides in length that is processed by the Dicer enzyme to form the 21-24 nucleotide mature microRNA. In this case the mature sequence is excised from the 3' arm of the hairpin.

mir-101 microRNA precursor family
Predicted secondary structure and sequence conservation of mir-101
Identifiers
Symbol	mir-101
Rfam	RF00253
miRBase	MI0000103
miRBase family	MIPF0000046
Other data
RNA type	Gene; miRNA
Domain(s)	Eukaryota
GO	GO:0035195 GO:0035068
SO	SO:0001244
PDB structures	PDBe

Survival analysis shows that hsa-miR-101 is associated with survival in multiple breast cancer datasets.^[3]