Mir-451 microRNA

In molecular biology mir-451 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

mir-451
miR-451 microRNA secondary structure and sequence conservation
Identifiers
Symbol	mir-451
Rfam	RF00722
miRBase family	MIPF0000148
OMIM	612071
Other data
RNA type	microRNA
Domain(s)	Eukaryota; Vertebrata
PDB structures	PDBe

miR-451 regulates the drug-transporter protein P-glycoprotein, potentially promoting resistance to the chemotherapy drug Paclitaxel.^[1]

Applications

A proof-of-concept experiment has shown that miR-451, as well as mir-126 and mir-150, could be using in forensic science to distinguish between blood and saliva samples.^[2] This is made possible by different miRNA profiles of miRNAs in the different tissue types.^[2]