Mucin-6

Mucin-6 (MUC-6), also known as gastrin mucus-6 is a protein that is encoded in the human by the MUC6 gene.^[5] MUC6, along with MUC2, MUC5AC, and MUC5B, is located within the 11p15 chromosomal locus of chromosome 11. MUC6, along with MUC1, is expressed in normal pancreases.^[6]

MUC6
Identifiers
Aliases	MUC6, MUC-6, mucin 6, oligomeric mucus/gel-forming
External IDs	OMIM: 158374; MGI: 2663233; HomoloGene: 18768; GeneCards: MUC6; OMA:MUC6 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.5 Start 1,012,823 bp[1] End 1,036,718 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 F5|7 87.03 cM Start 141,633,456 bp[2] End 141,655,319 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas duodenum body of stomach gallbladder fundus sural nerve islet of Langerhans right lobe of liver right uterine tube canal of the cervix Top expressed in duodenum stomach neural layer of retina cerebellum tail of embryo skeletal muscle tissue cerebellar cortex human kidney bone marrow granulocyte More reference expression data BioGPS n/a
Gene ontology Molecular function extracellular matrix structural constituent Cellular component Golgi lumen extracellular region plasma membrane Biological process maintenance of gastrointestinal epithelium O-glycan processing stimulatory C-type lectin receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4588 353328 Ensembl ENSG00000283350 ENSG00000277281 ENSG00000184956 ENSG00000277518 ENSMUSG00000048191 UniProt Q6W4X9 Q80T03 Q0VAV1 RefSeq (mRNA) NM_005961 NM_181729 NM_001330001 NM_001368953 RefSeq (protein) NP_005952 NP_859418.1 NP_001316930 NP_001355882 Location (UCSC) Chr 11: 1.01 – 1.04 Mb Chr 7: 141.63 – 141.66 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

In the stomach it is expressed in the antrum, in the gastric mucosa in the body, and in the deeper mucous glands of the antrum.^[7]